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FECHAR

ETOXPT

Sobre o projeto

The occurrence of toxins typical from tropical environments in European Union (EU) temperate coastal waters has been sporadically reported in the past years, usually preceded by human intoxication episodes. Therefore, to avoid public health impacts, there is a need for adequate monitoring programs, establishing appropriate legislation, and optimizing effective methods for the analysis of these toxins. However, due to the very limited quantitative data and the lack of validated analytical methodology, the risk associated with exposure to emergent toxins in the EU is currently not possible to determine. In ETOXPT, we will assess the current situation on the incidence and routes of exposure of emergent toxins in Portuguese coastal waters using reliable LC-MS/MS methods.

 

This project has received funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement No 101003376.

Logo ETOXPT

Publicações

Main Project Publications

  1. Maria F. Pais; Flávia Carvalho; Magda Frade; Pedro Reis Costa; José Paulo da Silva; Ana Marçalo; Adelino V.M. Canário; Sandra Lage. "Circannual Prevalence of tetrodotoxins in trumpet shells: Sea stars as a possible source of contamination and Implications for food safety". Food Control (2025): https://doi.org/10.1016/j.foodcont.2025.111353
  2. Sandra Lage; Felicitas ten Brink; Adelino V. M. Canário; José P. Da Silva. "New Vectors of TTX Analogues in the North Atlantic Coast: The Edible Crabs Afruca tangeri and Carcinus maenas". Marine Drugs (2023): https://doi.org/10. 3390/md21060320.
  3. Sandra Lage; Inês I. Afonso; Pedro Reis Costa; Adelino V. M. Canário; José P. Da Silva. "Tissue accumulation of tetrodotoxin (TTX) and analogues in trumpet shell Charonia lampas". Food Additives & Contaminants: Part A (2023): https://doi.org/10.1080/19440049.2022.2148756.
  4. Sandra Lage; Pedro Reis Costa; Adelino V. M. Canário; José P. Da Silva. "LCHRMS Profiling of Paralytic Shellfish Toxins in Mytilus galloprovincialis after a Gymnodinium catenatum Bloom". Marine Drugs (2022): https://doi.org/10. 3390/md20110680.
  5. Lucía Soliño; Sea-Yong Kim; Alfredo López; Pablo Covelo; Sara Rydberg; Pedro Reis Costa; Sandra Lage. "No ß-N-Methylamino-L-alanine (BMAA) Was Detected in Stranded Cetaceans from Galicia (North-West Spain)". Journal of Marine Science and Engineering (2022): https://doi.org/10.3390/jmse10030314.
  6. Camila Q. V. Costa; Inês I. Afonso; Sandra Lage; Pedro Reis Costa; Adelino V. M. Canário; José P. Da Silva. "Quantitation Overcoming Matrix Effects of Lipophilic Toxins in Mytilus galloprovincialis by Liquid Chromatography-Full Scan High Resolution Mass Spectrometry Analysis (LC-HR-MS)". Marine Drugs 20 2 (2022): 143. https://doi.org/10.3390/md20020143

Other Project Publications

  1. Rita Cordeiro; Rúben Luz; Sandra Lage; Carina Menezes; Elsa Dias; Cintia Flores; Amélia Fonseca; Vítor Gonçalves. "Metabolomic and taxonomic characterization of Haloleptolyngbya lusitanica sp. nov . (Cyanobacteria, Synechococcales)". Phycologia (2024): https://doi.org/10.1080/00318884. 2024.2317252.
  2. Miguel Barbosa; Pedro Reis Costa; Helena David; Sandra Lage; Ana Amorim. "Effect of temperature on growth and yessotoxin production of Protoceratium reticulatum and Lingulodinium polyedra (Dinophyceae) isolates from the Portuguese coast (NE Atlantic)". Marine Environmental Research (2024): http: //dx.doi.org/10.1016/j.marenvres.2023.106321.
  3. Vanessa M. Lopes; Mélanie Court; Martim Costa Seco; Francisco O. Borges; Bernardo Vicente; Sandra Lage; Ana Catarina Braga; et al. "Gymnodinium catenatum Paralytic Shellfish Toxin Production and Photobiological Responses under Marine Heat Waves". Toxins (2023): https://doi.org/10. 3390/toxins1502015.7.

Coordenação do CCMAR

Financiamento

HORIZON 2020