NanoReproTox.: Desvendando os impactos ecológicos da toxicidade de nanopartículas na reprodução de organismos marinhos

NanoReproTox

NanoReproTox.: Desvendando os impactos ecológicos da toxicidade de nanopartículas na reprodução de organismos marinhos

Datas

28.09.2018 - 27.09.2022

Grupos de Investigação

Aquaculture Research Group

Entidade Coordenadora

Universidade de Aveiro

Coordenação do CCMAR

Elsa Cabrita

Referência

ALG-01-0145-FEDER-030908

Agencias de financiamento

FCT - Fundação para a Ciência e Tecnologia

Orçamento Total

235272.00 €

Orçamento do CCMAR

34780.68€

link NRT

Atividades

The objective of the project is to evaluate the reprotoxic potential of nanoparticles (NPs) of titanium dioxide (TiO2) and silver (Ag), in gametes and gonads of marine organisms (bivalves and fish). Uncovering the toxic potential of these NPs for marine organisms will allow the creation of mitigation strategies, promoting the preservation of aquatic resources. The project was developed in 2 complementary phases: ex vivo tests (direct exposure of spermatozoa to NPs, in order to evaluate the effects after the release of gametes into the water) and in vivo tests (exposure via water of juvenile organisms, evaluating the influence of NPs on gonad development and gametogenesis). The results obtained in ex vivo assays indicate low susceptibility of sea bream sperm to these NPs. However, oyster gametes suggest being more susceptible to TiO2 NP than sea bream (Ag NP under evaluation).

Publicações

Fernández-García F, Carvalhais A, Marques A, Oliveira IB, Guilherme S, Oliveira H, Oliveira CCV, Cabrita E, Asturiano JF, Pacheco M, Mieiro C, 2023. Silver nanoparticles and silver ions indistinguishably decrease sperm motility in Pacific oysters (Magallana gigas) after short-term direct exposure. Environmental Toxicology and Pharmacology 101, 104202. Q1. IF: 4.3. Doi: 10.1016/j.etap.2023.104202

Oliveira CCV, Ferrão L, Gallego V, Mieiro C, Oliveira IB, Carvalhais A, Pacheco M, Cabrita E. Exposure to silver and titanium dioxide nanoparticles at supra-environmental concentrations decreased sperm motility and affected spermatozoa subpopulations in gilthead seabream, Sparus aurata. Fish Physiology and Biochemistry, Epub ahead of print. PMID: 37436567. Q1. IF: 2.9. Doi: 10.1007/s10695-023-01218-0

Oliveira IB, Carvalhais A, Guilherme S, Oliveira H, Oliveira CCV, Ferrão L, Cabrita E, Pacheco M, Mieiro C, 2023. Shipping can be achieved but cargo arrives with damage - titanium dioxide nanoparticles affect the DNA of Pacific oyster sperm. Aquatic Toxicology 258, 106446. Q1. IF: 4.5. Doi: 10.1016/j.aquatox.2023.106446

Carvalhais A, Oliveira IB, Oliveira H, Oliveira CCV, Ferrão L, Cabrita E, Asturianos JF, Guilherme S, Pacheco M, Mieiro CL, 2022. Ex vivo exposure to titanium dioxide and silver nanoparticles mildly affect sperm of gilthead seabream (Sparus aurata) - A multiparameter spermiotoxicity approach. Marine Pollution Bulletin 177, 113487. Q1. IF: 5.8. Doi: 10.1016/j.marpolbul.2022.113487