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 ORGANIC REACTIVITY AND MEDICINAL CHEMISTRY

OrgMedChem

OrgMedChem group_photo

Organic Reactivity and Medicinal Chemistry

Group leaders
Maria de Lurdes dos Santos Cristiano

The group is dedicated to the development of heterocyclic compounds applicable in medicine, environmental remediation, or aquaculture/fisheries, as well as investigating the structure, reactivity and activity of compounds obtained from synthesis or natural sources.

The group applies the methods and tools of Physical Organic Chemistry and Medicinal Chemistry to investigate structure-reactivity-activity relationships of selected compounds from biologically relevant chemotypes. We aim to contribute to the elucidation of interactions between compounds and their biological targets, gathering instrumental information for rational drug design and optimization.

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Also, the group has directed its research towards marine biotoxins (paralytic shellfish poisoning and diarrheic shellfish poisoning toxins, PSP and DSP, respectively), focusing on the development and optimization of non-toxic composites for the detoxification of marine aquatic systems.

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Research topics we are involved in:

  • Tackling pollution (Ocean Health – Protecting)
  • Sustainable aquaculture (Ocean Wealth – Exploring)
  • Blue biotechnology (Ocean Wealth – Exploring)
  • Food technologies (Ocean Wealth – Exploring)

 

 

Recent projects we are involved in:

Link: BEAP-MAR | Blue Bioeconomy in the Atlantic Area

Link: Descontaminação de moluscos bivalves, contaminados com biotoxinas marinhas, durante o processo de depuração – MAR-01.03.01-FEAMP-0049 (ualg.pt)